About 19km north of Sepupa (over 37km south of Shakawe) there's an unmarked turning (GPS: NXTURN) onto a vague track through the bush which leads northeast, about 5.5km from the main road, to Nxamaseri Lodge (GPS: NXAMAS). This is little more than a number of confusing tracks in the deep sand which initially head slightly left of the straight-line direction to the lodge, before finally bending right.

If you're approaching from the north this is about 21.5km south of the Somachima Veterinary Fence (GPS: VET-SA). After 10km you'll pass a slight rise marked by a sign as 'Tsodilo View' (GPS: TSVIEW). From here, on a clear day, you can see the hills to the southwest. Less than 3km south of this viewpoint you'll pass a sign to Nxamaseri, which leads to the village of the same name. The camp's unmarked turning is almost 9km south of this.

Nxamaseri will only accept advanced bookings, and it is surrounded by water for most of the year. So you always need to make advance arrangements to stay here. You'll usually be met if you're arriving by vehicle, and a boat and mokoro are often needed to ferry you the final few kilometres – so this is not a lodge to try and drop into unannounced.