It's fairly easy to get your bearings in Kasane. The Chobe River meanders roughly from east to west. This is the border with Namibia. A road shadows its course near its southern bank, the Botswana side. Kasane is a fairly linear town, spread out along that road. Most of the visitor's lodges stand on the river bank, accessed by short side-roads.
One tar road loops around away from town and the river to reach Ngoma, the border with Namibia. This actually cuts inland through the Chobe National Park, though isn't usually of interest for game viewing. A spur from this leads north, down the sandy game-viewing roads beside the Chobe riverfront. Another tar road heads south and slightly west before bending more east and heading towards Nata and the rest of the Eastern Corridor area. The latter offers the only 2WD access to the rest of Botswana.
There are few good maps of Kasane or its environs, perhaps because it's such an easy town to find your way about. For Chobe National Park, you need the excellent Shell map, by Veronica Roodt. This is usually available from African Easel bookshop, in the Audi Centre near Barclays.